The Professor's Rubik's Cube is the 5x5 version of the famous Rubik's Cube. The 5x5 Rubik's Cube is not for the faint of heart and is the most complex of all the Rubik's Cubes. However, knowing how to solve the 3x3 cube and the 4x4 cube will help you a lot. The total number of permutations for the 5x5 Cube has been calculated to be 283 duodecillion on the long scale or 283 trevigintillion on the short scale.